File Name: nucleic acids in chemistry and biology .zip
The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved.
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This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, Principles of Nucleic Acid Structure includes an introduction to technical lingo used to describe nucleic acid structure and conformations roll, slide, twist, buckle, etc.
Last reviewed: November An acidic, chainlike biological macromolecule consisting of multiple repeated units of phosphoric acid, sugar, and purine and pyrimidine bases. Nucleic acids Fig.
The reversible and noncovalent nature of the interactions governing the structure and binding properties of nucleic acids mean that the fields of supramolecular chemistry and nucleic acid chemistry are closely intertwined. Indeed, the high fidelity and programmable molecular recognition properties of DNA have Indeed, the high fidelity and programmable molecular recognition properties of DNA have long been the source of inspiration to many a supramolecular chemist in designing molecular assemblies that are both discrete in shape and dynamic in nature.
Nucleic acids are the biopolymers , or large biomolecules , essential to all known forms of life. They are composed of nucleotides , which are the monomers made of three components: a 5-carbon sugar , a phosphate group and a nitrogenous base. If the sugar is a compound ribose , the polymer is RNA ribonucleic acid ; if the sugar is derived from ribose as deoxyribose , the polymer is DNA deoxyribonucleic acid. Nucleic acids are naturally occurring chemical compounds that serve as the primary information-carrying molecules in cells. They play an especially important role in directing protein synthesis. Nucleic acids are found in abundance in all living things, where they create, encode, and then store information of every living cell of every life-form on Earth.
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